AGENT-BASED ANALYSIS OF CONTAGION EVENTS ACCORDING TO SOURCING LOCATIONS


The Microtubule Minus-End Binding Protein Patronin Is Required for the Epithelial Remodeling in the Drosophila Abdomen

In the developing Drosophila abdomen, the Earrings epithelial tissue displays extensive cytoskeletal remodeling.In stark contrast to the spatio-temporal control of the actin cytoskeleton, the regulation of microtubule architecture during epithelial morphogenesis has remained opaque.In particular, its role in cell motility remains unclear.Here, we s

read more

Combination of farnesyl-transferase inhibition with KRAS G12D targeting breaks down therapeutic resistance in pancreatic cancer

Pancreatic adenocarcinoma is one of the deadliest forms of cancer with no effective therapeutic options.A KRAS mutation can be found in up to 90% of all pancreatic tumors, making it a promising therapeutic target.The introduction of new KRAS inhibitors has been a milestone in the history of KRAS mutant tumors; however, therapeutic resistance limits

read more